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# CITATION file created with {cffr} R package
# See also: https://docs.ropensci.org/cffr/
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cff-version: 1.2.0
message: 'To cite package "gwas2crispr" in publications use:'
type: software
license: MIT
title: 'gwas2crispr: GWAS-to-CRISPR Data Pipeline for High-Throughput SNP Target Extraction'
version: 0.1.5
identifiers:
- type: doi
  value: 10.32614/CRAN.package.gwas2crispr
abstract: 'Provides a reproducible pipeline to conduct genome-wide association studies
  (GWAS) and extract single-nucleotide polymorphisms (SNPs) for a human trait or disease.
  Given aggregated GWAS dataset(s) and a user-defined significance threshold, the
  package retrieves significant SNPs from the GWAS Catalog using supported trait identifiers,
  annotates their gene context, and can write a harmonised metadata table in comma-separated
  values (CSV) format, genomic intervals in the Browser Extensible Data (BED) format,
  and sequences in the FASTA (text-based sequence) format with user-defined flanking
  regions for clustered regularly interspaced short palindromic repeats (CRISPR) guide
  design. The existing efo_id argument is retained for backward compatibility. The
  package prepares computational artifacts for downstream workflows; it does not perform
  biological causality testing, clinical interpretation, therapeutic design, or wet-lab
  validation. For details on the resources and methods see: Buniello et al. (2019)
  <https://doi.org/10.1093/nar/gky1120>; Sollis et al. (2023) <https://doi.org/10.1093/nar/gkac1010>;
  Jinek et al. (2012) <https://doi.org/10.1126/science.1225829>.'
authors:
- family-names: Mohammed
  given-names: Othman S. I.
  email: admin@leopard.ly
preferred-citation:
  type: manual
  title: 'gwas2crispr: GWAS-to-CRISPR Data Pipeline for High-Throughput SNP Target
    Extraction'
  authors:
  - family-names: Mohammed
    given-names: Othman S. I.
    email: admin@leopard.ly
  year: '2026'
  notes: R package version 0.1.5
  url: https://github.com/leopard0ly/gwas2crispr
repository: https://leopard0ly.r-universe.dev
repository-code: https://github.com/leopard0ly/gwas2crispr
commit: 9a362057d7cba96729bfdb40188cfe4fd61f8700
url: https://github.com/leopard0ly/gwas2crispr
date-released: '2026-06-02'
contact:
- family-names: Mohammed
  given-names: Othman S. I.
  email: admin@leopard.ly