https://leopard0ly.r-universe.devRecent package updates in leopard0lyR-universehttps://github.com/leopard0ly.pnghttps://leopard0ly.r-universe.devTue, 02 Jun 2026 11:51:22 GMTadmin@leopard.ly (Othman S. I. Mohammed)Provides a reproducible pipeline to conduct genome-wide association studies (GWAS) and extract single-nucleotide polymorphisms (SNPs) for a human trait or disease. Given aggregated GWAS dataset(s) and a user-defined significance threshold, the package retrieves significant SNPs from the GWAS Catalog using supported trait identifiers, annotates their gene context, and can write a harmonised metadata table in comma-separated values (CSV) format, genomic intervals in the Browser Extensible Data (BED) format, and sequences in the FASTA (text-based sequence) format with user-defined flanking regions for clustered regularly interspaced short palindromic repeats (CRISPR) guide design. The existing efo_id argument is retained for backward compatibility. The package prepares computational artifacts for downstream workflows; it does not perform biological causality testing, clinical interpretation, therapeutic design, or wet-lab validation. For details on the resources and methods see: Buniello et al. (2019) <doi:10.1093/nar/gky1120>; Sollis et al. (2023) <doi:10.1093/nar/gkac1010>; Jinek et al. (2012) <doi:10.1126/science.1225829>.https://github.com/r-universe/leopard0ly/actions/runs/28580110441Tue, 02 Jun 2026 11:51:22 GMTgwas2crispr0.1.5successhttps://leopard0ly.r-universe.devhttps://github.com/leopard0ly/gwas2crisprgwas2crispr.Rmdgwas2crispr.htmlgwas2crispr: From GWAS to CRISPR-ready Files2025-07-28 02:21:452026-06-02 11:39:48